Research Library
The following scientific abstracts have been reviewed by the Dr. Eliaz staff for relevance to the ingredient Indole-3-carbinol. Click on any of the following abstract titles to see the details of the abstract.
Title: Anti-carcinogenic and anti-metastatic properties of indole-3-carbinol in prostate cancer.
Authors: Garikapaty VP, Ashok BT, Chen YG, Mittelman A, Iatropoulos M, Tiwari RK.
Journal: Oncol Rep. 2005 Jan;13(1):89-93.
Title: Indole-3-carbinol is a negative regulator of estrogen.
Authors: Auborn KJ, Fan S, Rosen EM, Goodwin L, Chandraskaren A, Williams DE, Chen D, Carter TH.
Journal: J Nutr. 2003 Jul;133(7 Suppl):2470S-2475S
Title: Indole-3-carbinol and 3-3'-diindolylmethane antiproliferative signaling pathways control cell-cycle gene transcription in human breast cancer cells by regulating promoter-Sp1 transcription factor interactions.
Authors: Firestone GL, Bjeldanes LF.
Journal: J Nutr. 2003 Jul;133(7 Suppl):2448S-2455S.
Title: Indole-3-carbinol and 3,3'-diindolylmethane induce apoptosis in human prostate cancer cells.
Authors: Nachshon-Kedmi M, Yannai S, Haj A, Fares FA.
Journal: Food Chem Toxicol. 2003 Jun;41(6):745-52.
Title: Bcl-2 family-mediated apoptotic effects of 3,3'-diindolylmethane (DIM) in human breast cancer cells.
Authors: Hong C, Firestone GL, Bjeldanes LF.
Journal: Biochem Pharmacol 2002 Mar 15;63(6):1085-1097
Title: Placebo-controlled trial of indole-3-carbinol in the treatment of CIN.
Authors: Bell MC; Crowley-Nowick P; Bradlow HL; Sepkovic DW Schmidt-Grimminger D; Howell P; Mayeaux EJ; Tucker A; Turbat-Herrera EA Mathis JM
Journal: Gynecol Oncol 2000 Aug;78(2):123-9
Title: Suppression of breast cancer invasion and migration by indole-3-carbinol: associated with up-regulation of BRCA1 and E-cadherin/catenin complexes [In Process Citation]
Authors: Meng Q; Qi M; Chen DZ; Yuan R; Goldberg ID; Rosen EM Auborn K; Fan S
Journal: J Mol Med 2000;78(3):155-65
Title: Ligand-independent activation of estrogen receptor function by 3, 3'-diindolylmethane in human breast cancer cells.
Authors: Riby JE; Chang GH; Firestone GL; Bjeldanes LF
Journal: Biochem Pharmacol 2000 Jul 15;60(2):167-77
Title: Indole-3-carbinol as a chemopreventive agent in 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP) carcinogenesis: inhibition of PhIP-DNA adduct formation, acceleration of PhIP metabolism, and induction of cytochrome P450 in female F344 ra
Authors: He YH; Friesen MD; Ruch RJ; Schut HA
Journal: Food Chem Toxicol 2000 Jan;38(1):15-23
Title: Multifunctional aspects of the action of indole-3-carbinol as an antitumor agent.
Authors: Bradlow HL; Sepkovic DW; Telang NT; Osborne MP
Journal: Ann N Y Acad Sci 1999;889:204-13
Title: The major cyclic trimeric product of indole-3-carbinol is a strong agonist of the estrogen receptor signaling pathway.
Authors: Riby JE; Feng C; Chang YC; Schaldach CM Firestone GL; Bjeldanes LF
Journal: Biochemistry 2000 Feb 8;39(5):910-8
Title: Induction of apoptosis in MCF-7 cells by indol-3-carbinol is independent of p53 and bax.
Authors: Ge X; Fares FA; Yannai S
Journal: Anticancer Res 1999 Jul-Aug;19(4B):3199-203
Title: Chemoprevention of breast cancer.
Authors: Osborne MP
Journal: Surg Clin North Am 1999 Oct;79(5):1207-21
Title: [The significance of estrogen metabolism for hormone-dependent neoplasms from the clinical-pharmacological viewpoint]
Authors: Lippert TH; Seeger H; Mueck AO
Journal: Arzneimittelforschung 1999 Aug;49(8):649-62
Title: Anti-estrogenic activities of indole-3-carbinol in cervical cells: implication for prevention of cervical cancer.
Authors: Yuan F; Chen DZ; Liu K; Sepkovic DW; Bradlow HL Auborn K
Journal: Anticancer Res 1999 May-Jun;19(3A):1673-80
Title: Indole-3-carbinol and tamoxifen cooperate to arrest the cell cycle of MCF-7 human breast cancer cells.
Authors: Cover CM; Hsieh SJ; Cram EJ; Hong C; Riby JE Bjeldanes LF; Firestone GL
Journal: Cancer Res 1999 Mar 15;59(6):1244-51
Title: Indole-3-carbinol and tamoxifen cooperate to arrest the cell cycle of MCF-7 human breast cancer cells.
Authors: Cover CM; Hsieh SJ; Cram EJ; Hong C; Riby JE Bjeldanes LF; Firestone GL
Journal: Cancer Res 1999 Mar 15;59(6):1244-51
Title: Anti-estrogenic activities of indole-3-carbinol in cervical cells: implication for prevention of cervical cancer.
Authors: Yuan F; Chen DZ; Liu K; Sepkovic DW; Bradlow HL Auborn K
Journal: Anticancer Res 1999 May-Jun;19(3A):1673-80
Title: [The significance of estrogen metabolism for hormone-dependent neoplasms from the clinical-pharmacological viewpoint]
Authors: Lippert TH; Seeger H; Mueck AO
Journal: Arzneimittelforschung 1999 Aug;49(8):649-62
Title: Chemoprevention of breast cancer.
Authors: Osborne MP
Journal: Surg Clin North Am 1999 Oct;79(5):1207-21
Title: Induction of apoptosis in MCF-7 cells by indol-3-carbinol is independent of p53 and bax.
Authors: Ge X; Fares FA; Yannai S
Journal: Anticancer Res 1999 Jul-Aug;19(4B):3199-203
Title: The major cyclic trimeric product of indole-3-carbinol is a strong agonist of the estrogen receptor signaling pathway.
Authors: Riby JE; Feng C; Chang YC; Schaldach CM Firestone GL; Bjeldanes LF
Journal: Biochemistry 2000 Feb 8;39(5):910-8
Title: Multifunctional aspects of the action of indole-3-carbinol as an antitumor agent.
Authors: Bradlow HL; Sepkovic DW; Telang NT; Osborne MP
Journal: Ann N Y Acad Sci 1999;889:204-13
Title: Indole-3-carbinol as a chemopreventive agent in 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP) carcinogenesis: inhibition of PhIP-DNA adduct formation, acceleration of PhIP metabolism, and induction of cytochrome P450 in female F344 ra
Authors: He YH; Friesen MD; Ruch RJ; Schut HA
Journal: Food Chem Toxicol 2000 Jan;38(1):15-23
Title: Ligand-independent activation of estrogen receptor function by 3, 3'-diindolylmethane in human breast cancer cells.
Authors: Riby JE; Chang GH; Firestone GL; Bjeldanes LF
Journal: Biochem Pharmacol 2000 Jul 15;60(2):167-77
Title: Suppression of breast cancer invasion and migration by indole-3-carbinol: associated with up-regulation of BRCA1 and E-cadherin/catenin complexes [In Process Citation]
Authors: Meng Q; Qi M; Chen DZ; Yuan R; Goldberg ID; Rosen EM Auborn K; Fan S
Journal: J Mol Med 2000;78(3):155-65
Title: Placebo-controlled trial of indole-3-carbinol in the treatment of CIN.
Authors: Bell MC; Crowley-Nowick P; Bradlow HL; Sepkovic DW Schmidt-Grimminger D; Howell P; Mayeaux EJ; Tucker A; Turbat-Herrera EA Mathis JM
Journal: Gynecol Oncol 2000 Aug;78(2):123-9