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Research Library

The following scientific abstracts have been reviewed by the Dr. Eliaz staff for relevance to the ingredient Alpha-lipoic acid. Click on any of the following abstract titles to see the details of the abstract.

Title: Effect of Combined Treatment With alpha-Lipoic Acid and Acetyl-L-Carnitine on Vascular Function and Blood Pressure in Patients With Coronary Artery Disease.
Authors: McMackin CJ, Widlansky ME, Hamburg NM, Huang AL, Weller S, Holbrook M, Gokce N, Hagen TM, Keaney JF Jr, Vita JA.
Journal: J Clin Hypertens (Greenwich). 2007 Apr;9(4):249-55.

Title: Efficacy of alpha-Lipoic Acid Against Diabetic Cataract in Rat.
Authors: Kojima M, Sun L, Hata I, Sakamoto Y, Sasaki H, Sasaki K.
Journal: Jpn J Ophthalmol. 2007 Jan-Feb;51(1):10-3. Epub 2007 Feb 9.

Title: Oral treatment with alpha-lipoic acid improves symptomatic diabetic polyneuropathy: the SYDNEY 2 trial.
Authors: Ziegler D, Ametov A, Barinov A, Dyck PJ, Gurieva I, Low PA, Munzel U, Yakhno N,Raz I, Novosadova M, Maus J, Samigullin R.
Journal: Diabetes Care. 2006 Nov;29(11):2365-70.

Title: Lipoic acid as a novel treatment for Alzheimer's disease and related dementias.
Authors: Holmquist L, Stuchbury G, Berbaum K, Muscat S, Young S, Hager K, Engel J, Munch G.
Journal: Pharmacol Ther. 2007 Jan;113(1):154-64. Epub 2006 Sep 20.

Title: Alpha-lipoic acid suppresses the development of collagen-induced arthritis and protects against bone destruction in mice.
Authors: Lee EY, Lee CK, Lee KU, Park JY, Cho KJ, Cho YS, Lee HR, Moon SH, Moon HB, Yoo B.
Journal: Rheumatol Int. 2006 Aug 31; [Epub ahead of print]

Title: Safety evaluation of alpha-lipoic acid (ALA).
Authors: Cremer DR, Rabeler R, Roberts A, Lynch B.
Journal: Regul Toxicol Pharmacol. 2006 Oct;46(1):29-41. Epub 2006 Aug 14.

Title: A phase II study with antioxidants, both in the diet and supplemented, pharmaconutritional support, progestagen, and anti-cyclooxygenase-2 showing efficacy and safety in patients with cancer-related anorexia/cachexia and oxidative stress.
Authors: Mantovani G, Maccio A, Madeddu C, Gramignano G, Lusso MR, Serpe R, Massa E, Astara G, Deiana L.
Journal: Cancer Epidemiol Biomarkers Prev. 2006 May;15(5):1030-4.Click here to read

Title: The long-term survival of a patient with pancreatic cancer with metastases to the liver after treatment with the intravenous alpha-lipoic acid/low-dose naltrexone protocol.
Authors: Berkson BM, Rubin DM, Berkson AJ.
Journal: Integr Cancer Ther. 2006 Mar;5(1):83-9.

Title: Alpha-lipoic acid modulates ovarian surface epithelial cell growth.
Authors: Vig-Varga E, Benson EA, Limbil TL, Allison BM, Goebl MG, Harrington MA.
Journal: Gynecol Oncol. 2006 Mar 27

Title: Trans fatty acids promote the growth of some Lactobacillus strains.
Authors: Endo Y, Kamisada S, Fujimoto K, Saito T.
Journal: J Gen Appl Microbiol. 2006 Feb;52(1):29-35.

Title: Lipoic acid improves glucose utilisation and prevents protein glycation and AGE formation.
Authors: Thirunavukkarasu V, Anitha Nandhini AT, Anuradha CV.
Journal: Pharmazie. 2005 Oct;60(10):772-5.

Title: Chemoprotective effect of lipoic acid against cyclophosphamide-induced changes in the rat sperm.
Authors: Selvakumar E, Prahalathan C, Sudharsan PT, Varalakshmi P.
Journal: Toxicology. 2005 Oct 1

Title: Endogenous production of lipoic acid is essential for mouse development.
Authors: Yi X, Maeda N.
Journal: Mol Cell Biol. 2005 Sep;25(18):8387-92.

Title: Protective Effect of {alpha}-Lipoic Acid in Lipopolysaccharide-Induced Endothelial Fractalkine Expression.
Authors: Sung MJ, Kim W, Ahn SY, Cho CH, Koh GY, Moon SO, Hoon Kim D, Lee S, Kang KP, Jang KY, Park SK.
Journal: Circ Res. 2005 Sep 15

Title: Nutritional therapy improves function and complements corticosteroid intervention in mdx mice.
Authors: Payne ET, Yasuda N, Bourgeois JM, Devries MC, Rodriguez MC, Yousuf J, Tarnopolsky MA.
Journal: Muscle Nerve. 2005 Sep 7;

Title: alpha-Lipoic acid supplementation inhibits oxidative damage, accelerating chronic wound healing in patients undergoing hyperbaric oxygen therapy.
Authors: Alleva R, Nasole E, Donato FD, Borghi B, Neuzil J, Tomasetti M.
Journal: Biochem Biophys Res Commun. 2005 Jul 29;333(2):404-10.

Title: Alpha-lipoic acid increases insulin sensitivity by activating AMPK in skeletal muscle.
Authors: Lee WJ, Song KH, Koh EH, Won JC, Kim HS, Park HS, Kim MS, Kim SW, Lee KU, Park JY.
Journal: Biochem Biophys Res Commun. 2005 Jul 8;332(3):885-91.

Title: Treatment for diabetic mononeuropathy with alpha-lipoic acid.
Authors: Tankova T, Cherninkova S, Koev D.
Journal: Int J Clin Pract. 2005 Jun;59(6):645-50.

Title: Brain regional responses in antioxidant system to alpha-lipoic acid in arsenic intoxicated rat.
Authors: Shila S, Kokilavani V, Subathra M, Panneerselvam C.
Journal: Toxicology. 2005 May 15;210(1):25-36.

Title: The Protective Effect of Alpha-Lipoic Acid against Oxidative Damage in Rabbit Conjunctiva and Cornea Exposed to Ultraviolet Radiation.
Authors: Demir U, Demir T, Ilhan N.
Journal: Ophthalmologica. 2005;219(1):49-53.

Title: alpha-Lipoic acid prevents diabetes mellitus in diabetes-prone obese rats.
Authors: Song KH, Lee WJ, Koh JM, Kim HS, Youn JY, Park HS, Koh EH, Kim MS, Youn JH, Lee KU, Park JY.
Journal: Biochem Biophys Res Commun. 2004 Dec 31;326(1):197-202.

Title: Alpha-lipoic acid in the treatment of autonomic diabetic neuropathy (controlled, randomized, open-label study).
Authors: Tankova T, Koev D, Dakovska L.
Journal: Rom J Intern Med. 2004;42(2):457-64.

Title: Effect of long-term administration of alpha-lipoic acid on retinal capillary cell death and the development of retinopathy in diabetic rats.
Authors: Kowluru RA, Odenbach S.
Journal: Diabetes. 2004 Dec;53(12):3233-8.

Title: The sensory symptoms of diabetic polyneuropathy are improved with alpha-lipoic acid: the SYDNEY trial.
Authors: Ametov AS, Barinov A, Dyck PJ, Hermann R, Kozlova N, Litchy WJ, Low PA, Nehrdich D, Novosadova M, O'Brien PC, Reljanovic M, Samigullin R, Schuette K, Strokov I, Tritschler HJ, Wessel K, Yakhno N, Ziegler D; SYDNEY Trial Study Group.
Journal: Diabetes Care. 2003 Mar;26(3):770-6.

Title: Inhibition of glucose production and stimulation of bile flow by R (+)-alpha-lipoic acid enantiomer in rat liver.
Authors: Zhou JR, Yu L, Zhong Y, Nassr RL, Franke AA, Gaston SM, Blackburn GL.
Journal: Prostate 2002 Oct 1;53(2):143-53

Title: Lead induced oxidative damage and its response to combined administration of alpha-lipoic acid and succimers in rats.
Authors: Pande M, Flora SJ.
Journal: Toxicology 2002 Aug 15;177(2-3):187-96

Title: Uptake, recycling, and antioxidant actions of alpha-lipoic acid in endothelial cells.
Authors: Jones W, Li X, Qu Z, Perriott L, Whitesell RR, May JM.
Journal: Free Radic Biol Med 2002 Jul 1;33(1):83-93

Title: Memory loss in old rats is associated with brain mitochondrial decay and RNA/DNA oxidation: partial reversal by feeding acetyl-L-carnitine and/or R-alpha -lipoic acid.
Authors: Liu J, Head E, Gharib AM, Yuan W, Ingersoll RT, Hagen TM, Cotman CW, Ames BN.
Journal: Proc Natl Acad Sci U S A. 2002 Feb 19;99(4):2356-61.

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