Research Library
Influence of PADMA 28 and thymus extract on clinical and laboratory parameters of children with juvenile chronic arthritis
Authors: Brzosko WJ, Jankowski A, Prusek W, Ollendiek H
Source: Int. Journal of Immunotherapy 1991;VII/3:143-147
Nineteen children with juvenile chronic arthritis (JCA), divided into two groups of 12 and 7 children, were treated with PADMA 28 and thymus extract, respectively. PADMA 28 (P28), a herbal remedy prepared according to an old lamaistic formula, is a definite immunocorrective remedy confirmed by in vivo and in vitro studies on animals and human subjects. Thymus extract (ThE), prepared as suppositories, was found to be a very effective immunoregulatory preparation when tested on human diverse chronic inflammatory diseases. The influence of P28 and ThE suppositories was evaluated after 6 weeks of treatment with P28 and after 4 weeks of therapy with ThE. P28 was given in a dose of two to four tablets daily, and ThE one suppository per day. It was found that the preparations positively influenced both clinical and laboratory parameters and thus may be used as an alternative (heterodox) to orthodox treatment. Besides their clinical efficacy, the preparations gave no side-effects and this is an additional important parameter which should encourage doctors to use them for the treatment of patients with JCA.