Research Library
Evolutionary perspective on dietary intake of fibre and colorectal cancer.
Authors: Leach JD.
Source: Eur J Clin Nutr. 2006 Jul 19
From an evolutionary perspective, the ongoing discussion of fibres role in colorectal cancer is possibly limited by the overall low intake of fibre across study groups. Our ancestral diet consistently included a diverse range of plants that regularly contributed up to and often >100 g/day of dietary fibre. Importantly, this diversity assured that, owing to a range of physical and chemical structures, a steady flow of fermentable substrates promoted metabolic activity into the distal regions of the colon.European Journal of Clinical Nutrition advance online publication, 19 July 2006; doi:10.1038/sj.ejcn.1602486.