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The Effect of Padma 28, a Traditional Tibetan Herbal Preparation, on Human Neutrophil Function.
Authors: Matzner Y, Sallon S
Source: J Clin Lab Immun 1995;46:13-23
Human neutrophils were studied in vitro in the presence of the herbal preparation Padma 28. At concentrations higher than 0.3 mg/ml, the Padma 28 induced 02 production in unstimulated neutrophils. At lower concentrations, 02 production was inhibited in phorbol myristate acetate (PMA) stimulated cells. Lysozyme release by PMA and opsonized zymosan-stimulated cells was inhibited by Padma 28 at a concentration dependent manner. On the other hand, random and directed migration and adhesion to nylon fibers were not affected. These results suggest that Padma 28 may have anti-inflammatory activity whose mechanism remains to be elucidated.